ISO 23196:2022

Water quality — Calculation of biological equivalence (BEQ) concentrations
Autor: ISO
Código ICS: 13.060.70


This document specifies the derivation of biological equivalence (BEQ) concentrations for results of in vitro bioassays which are based on measuring effects on a biological process such as enzyme induction or cellular growth. The concept described here can be used for any biological assay after the proof of its applicability.To derive BEQ concentrations, the effect on a biological process caused by a sample – i.e. the activity of the sample – is expressed in terms of a concentration of a reference compound which results in an equivalent effect on the process. The term "sample" used in this document addresses environmental samples as well as defined mixtures and pure compounds used as test item in a bioassay. BEQ concentrations can be derived for environmental water samples, extracts of environmental water samples including tap water or solutions of pure chemicals or mixtures of chemicals.

Especificaciones de la Norma
Fecha de Publicación 07/02/2022
Título Secundario Titre manque
Páginas Técnicas 18
Idioma Inglés